The artist has given the complete sum of his £25k honor cash to the trust for venues, which works to preserve the United Kingdom's small concert spaces.
He was given the prize on October 16 as his third album the album was named the outstanding release of the last 12 months.
He has decided to donate the funds to the MVT, in recognition of the essential function grassroots venues fulfilled in his early career.
"I would not have achieved my current career if it wasn't for all the gigs I performed around the region, and elsewhere, when I was just getting going," said Sam Fender. "These locations are renowned, but they are in difficulty."
Beginning in 2023, more than 150 of these locations have permanently closed – about one-sixth of the total UK scene.
Recently, major artists like Pulp, Coldplay, Katy Perry and Sheeran have all backed the MVT in its efforts to keep the scene afloat, by including a minor surcharge to their ticket prices, which benefits local stages.
Sam Fender also took part, collecting more than £100,000 on his live tour to help 38 local spots across the UK.
These funds assisted spaces that were dealing with potential shutdown due to challenges stemming from water damage, fire incidents and personal losses, as well as permit problems, court cases and sound issues.
Other venues were granted monetary aid in upgrading amenities and gear that positively impacted musicians and audiences.
"The idea that money from performances in large arenas supports the independent spots, where it all starts for musicians like me, is just sensible," Sam Fender has commented.
He is among several artists to give his Mercury Prize winnings to charitable organizations.
Back when they received the award in 1996 for their album their work, lead singer Cocker stated that the act would give their winnings to the organization War Child.
During 2002, artist Ms Dynamite shared her bounty between a few charities, such as the NSPCC and a Sickle Cell charity.
"And I donated a grand to Highgate Newtown, to their gymnastics class, because I practiced gymnastics when I was younger and they lacked better apparatus," Ms Dynamite told a publication.
In recent years, the band gave their funds to the local youth club that supported their band, as well as other local music groups.
Also 1994 winners M People gave their prize to a MS organization after a acquaintance was found to have the illness.
"Winning was sufficient," stated singer Small. "The money was the bonus but we didn't need the cherry, because we had the honor. So our winning impacted somebody else's life."
In the past week, the trust revealed it had rescued several small stages in the South East, by placing them under community ownership.
One venue in Southampton and the second in Bristol were acquired under the public acquisition scheme, which is funded by a national body and music fans who acquire "ownership units" in the buildings.
